Photo by Nikita Kachanovsky


Acerca del desajuste evolutivo

Aquí encontraras enlaces y toda la información adicional que vaya colgando referente al libro.


  ¿Qué características debe cumplir una dieta para ser saludable?

 Importance of Nutrients and Nutrient Metabolism on Human Health
 Biochemistry, Essential Amino Acids
 Discovery of essential fatty acids
 Food synergy: the key to a healthy diet

  Un pequeño inciso

 Human evolution. Human-like hand use in Australopithecus africanus

  Entrando en la sabana, territorio hostil

 Bone Marrow: A Source of Nutritionally Valuable Fats as Typified in the Femur of Ram and Bull
  Taphonomy of fossils from the hominin-bearing deposits at Dikika, Ethiopia

  Nuestro cerebro aumentó

 Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives
 Essential fatty acids as functional components of foods- a review
 Upper gastrointestinal (GI) pH in young, healthy men and women
 The evolution of the human trophic level during the Pleistocene

  Hacia el Mesolítico y Neolítico

 Evolution of the human brain: is bigger better?

  Cambios durante el neolítico

 Integrating nutrient bioavailability and co-production links when identifying sustainable diets: How low should we reduce meat consumption?
 The bioavailability of iron, zinc, protein and vitamin A is highly variable in French individual diets: Impact on nutrient inadequacy assessment and relation with the animal-to-plant ratio of diets
 Is There Such a Thing as "Anti-Nutrients"? A Narrative Review of Perceived Problematic Plant Compounds

  Cambios durante la Revolución Industrial

 The Importance of Maintaining a Low Omega-6/Omega-3 Ratio for Reducing the Risk of Autoimmune Diseases, Asthma, and Allergies
 Effect of Intermittent Fasting Diet on Glucose and Lipid Metabolism and Insulin Resistance in Patients with Impaired Glucose and Lipid Metabolism: A Systematic Review and Meta-Analysis
 Role of ketones, ketogenic diets and intermittent fasting in ICU
 The effect of fasting or calorie restriction on autophagy induction: A review of the literature

  El ratio entre los omegas y la inflamación crónica

 The importance of the ratio of omega-6/omega-3 essential fatty acids
 Essential fatty acids in visual and brain development
 Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases
 Understanding phospholipid function: Why are there so many lipids?
 Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids
 Omega-3 fatty acids and inflammatory processes: from molecules to man
 Systemic low-grade inflammation-associated lifestyle, diet, and genetic factors: A population-based cross-sectional study
  An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
 Essential fatty acids in fish physiology
 Importance of a balanced omega 6/omega 3 ratio for the maintenance of health: nutritional recommendations

  Corrigiendo el ratio de omegas

 Omega-3 fatty acids in inflammation and autoimmune diseases
 An Intricate Review on Nutritional and Analytical Profiling of Coconut, Flaxseed, Olive, and Sunflower Oil Blends
 alpha-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans
 Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio [corrected] of α-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort
 Algal supplementation of vegetarian eating patterns improves plasma and serum docosahexaenoic acid concentrations and omega-3 indices: a systematic literature review

  ¿Qué pasa con los suplementos de omega 3?

 Oxidation of Marine Omega-3 Supplements and Human Health
 The FDA's new advice on fish: it's complicated
 Omega-3 polyunsaturated fatty acids and vegetarian diets

  El intestino delgado

 Physiology of Intestinal Absorption and Secretion
  Intestinal barrier function

  La barrera intestinal

 Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
 The role of mucosal barriers in human gut health
 The role of enterocytes in the intestinal barrier function and antigen uptake

  La capa de enterocitos

 Enterocytes: active cells in tolerance to food and microbial antigens in the gut
 Proteomic analysis of the enterocyte brush border

  Uniones estrechas

 Tight Junction Structure and Function Revisited
 Enterocytes' tight junctions: From molecules to diseases
 Occludin and claudins in tight-junction strands: leading or supporting players?

  Zonulina, el regulador de las uniones estrechas

 What is gluten?
 Zonulin, regulation of tight junctions, and autoimmune diseases
 Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer
  Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function
 All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases
 Leaky Gut and Autoimmunity: An Intricate Balance in Individuals Health and the Diseased State

  Las células dendríticas

 Intestinal Dendritic Cells in Health and Gut Inflammation
 Dendritic cells in intestinal immune regulation

  Presentando antígenos

 Antigen-Presenting Cells: Potential of Proven und New Players in Immune Therapies
 Regulation of the immune response by antigen
 The HLA system: genetics, immunology, clinical testing, and clinical implications
 Dendritic cells as antigen presenting cells in vivo

  Nuestro Sistema Inmunitario aprende

 The innate and adaptive immune systems
 Histology, T-Cell Lymphocyte
 T Cell Activation

  Atacando nuestros propios tejidos

 Cytotoxic T lymphocytes and autoimmunity
 T Lymphocytes and Autoimmunity
 Stress as a trigger of autoimmune disease

  Yendo un poco más allá

 Tight junction modulation at the blood-brain barrier: Current and future perspectives
 Could serum zonulin be an intestinal permeability marker in diabetes kidney disease?
 Biomarkers of intestinal barrier function in multiple sclerosis are associated with disease activity
 C-type lectin-like receptor 2 and zonulin are associated with mild cognitive impairment and Alzheimer's disease
 Serum zonulin and claudin-5 levels in patients with schizophrenia
 Reviewing the Significance of Blood-Brain Barrier Disruption in Multiple Sclerosis Pathology and Treatment
 Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer
 Zonulin and blood-brain barrier permeability are dissociated in humans
 Alcohol-Induced Blood-Brain Barrier Impairment: An In Vitro Study
 Effects of ethanol and acetaldehyde on tight junction integrity: in vitro study in a three dimensional intestinal epithelial cell culture model
 Ethanol-induced activation of myosin light chain kinase leads to dysfunction of tight junctions and blood-brain barrier compromise

  Dieta libre de gluten

 Leaky Gut and Autoimmunity: An Intricate Balance in Individuals Health and the Diseased State

  Peligros de una dieta libre de gluten

 Nutritional quality and costs of gluten-free products: a case-control study of food products on the Norwegian marked

  Dieta paleo

 Effect of endocrine disruptor phytoestrogens on the immune system: Present and future
 Is There Such a Thing as "Anti-Nutrients"? A Narrative Review of Perceived Problematic Plant Compounds

  Dieta AIP

 Excessive intake of sugar: An accomplice of inflammation


 Mediterranean diet and health status: Active ingredients and pharmacological mechanisms
 Paleolithic Diet-Effect on the Health Status and Performance of Athletes?
 Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with All-Cause and Cause-Specific Mortality in Adults

  La Dieta carnívora

 Evolutionary Perspectives on Fat Ingestion and Metabolism in Humans
 Health effects associated with consumption of unprocessed red meat: a Burden of Proof study

  Características de la dieta carnívora

 The evolution of the human trophic level during the Pleistocene
 Mikhaila Peterson - 'Don't Eat That'
 Saponin toxicity as key player in plant defense against pathogens
 Protein, weight management, and satiety
 Snack Food, Satiety, and Weight

  ¿Qué es la biodisponibilidad?

 Bioavailability of Micronutrients From Nutrient-Dense Whole Foods: Zooming in on Dairy, Vegetables, and Fruits
 Fe and Zn in vitro bioavailability in relation to antinutritional factors in biofortified beans subjected to different processes
  Contribution of Dietary Oxalate and Oxalate Precursors to Urinary Oxalate Excretion
 Glucose modulates vitamin C transport in adult human small intestinal brush border membrane vesicles
 Tannins: current knowledge of food sources, intake, bioavailability and biological effects
  Phytate in foods and significance for humans: food sources, intake, processing, bioavailability, protective role and analysis
 Dietary Lectin exclusion: The next big food trend?
 Integrating nutrient bioavailability and co-production links when identifying sustainable diets: How low should we reduce meat consumption?
 Bioconversion of dietary provitamin A carotenoids to vitamin A in humans
  Bioavailability of vitamin D(2) and D(3) in healthy volunteers, a randomized placebo-controlled trial
 Vitamin K2 Needs an RDI Separate from Vitamin K1
 Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man
 Vitamin B-12: plant sources, requirements, and assay
 Carnitine Deficiency

  Dieta vegetariana

 Omega-3 polyunsaturated fatty acids and vegetarian diets
 The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature
 Vegetarians have a reduced skeletal muscle carnitine transport capacity
 Carnitine. The science behind a conditionally essential nutrient. Proceedings of a conference. March 25-26, 2004. Bethesda, Maryland, USA
 Effect of vegetarian diets on zinc status: a systematic review and meta-analysis of studies in humans

  Dieta cetogénica

 Physiology, Krebs Cycle
 Mitochondria in Health and Diseases
 Biochemistry, Glycolysis
 A parent's perspective on dietary treatments for epilepsy
 The ketogenic diet for infants: How long can you go?
 The Implication of Physiological Ketosis on The Cognitive Brain: A Narrative Review
 Medium-chain triglycerides in infant formulas and their relation to plasma ketone body concentrations
 A Ketogenic Diet is Effective in Improving Insulin Sensitivity in Individuals with Type 2 Diabetes
 Biochemistry, Gluconeogenesis

  Ayuno intermitente

 Short-term fasting induces profound neuronal autophagy
 Physiological changes during fasting in Ramadan